Oleclumab (INN;[1] development code MEDI9447) is a human monoclonal antibody targeting the ectonucleotidase CD73[2] that was designed for the treatment of pancreatic and colorectal and other cancers.[3]
This drug was developed by MedImmune/AstraZeneca.[4]
References
- ^ World Health Organization (2016). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 116" (PDF). WHO Drug Information. 30 (4).
- ^ Kowash RR, Akbay EA (2023). "Tumor intrinsic and extrinsic functions of CD73 and the adenosine pathway in lung cancer". Frontiers in Immunology. 14 1130358. doi:10.3389/fimmu.2023.1130358. PMC 10079876. PMID 37033953.
- ^ ClinicalTrial.gov for Oleclumab
- ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Oleclumab, American Medical Association.