Adaprolol is a potent beta-adrenergic antagonist.[1][2][3] The drug produces electrophysiologic effects, prolonging basic sinus cycle length and the refractory period of the His-Purkinje system and the ventricles of the heart.[4] It is a soft drug purposed for the treatment of glaucoma. The drug was designed to be quickly and easily metabolized, minimizing systemic activity through facile inactivation into an inactive metabolite.[3]
References
- ↑ "The Use of Common Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances: Alphabetical list of stems together with corresponding INNs". Archived from the original on March 7, 2012.
- ↑ Boder N, Elkoussi A, Zuobi K, Kovacs P (1996). "Synthesis and pharmacological activity of adaprolol enantiomers: a new soft drug for treating glaucoma". Journal of Ocular Pharmacology and Therapeutics. 12 (2): 115–22. doi:10.1089/jop.1996.12.115. PMID 8773927.
- 1 2 "NCATS Inxight Drugs — ADAPROLOL". drugs.ncats.io. Retrieved 2026-05-21.
- ↑ "Cardiac electrophysiologic effects of adaprolol maleate, a new β-blocker, in closed chest dogs". Life Sciences. 48 (16): 1519–1528. 1991-01-01. doi:10.1016/0024-3205(91)90276-H. ISSN 0024-3205.