2CE-5iPrO, also known as 5-iPrO-2C-E or as 2-methoxy-5-isopropoxy-4-ethylphenethylamine, is a psychedelic substituted phenethylamine derivative related to 2C-E, but with the 5-methoxy group extended to isopropoxy. Similar to related "tweetio" compounds such as 2CD-5EtO, it has a longer duration of action than 2C-E but is otherwise similar in activity, although it shows reduced anti-inflammatory actions.[1] The drug is a controlled substance in Canada under phenethylamine blanket-ban language.[2]

See also

References

  1. Flanagan TW, Billac GB, Landry AN, Sebastian MN, Cormier SA, Nichols CD (April 2021). "Structure-Activity Relationship Analysis of Psychedelics in a Rat Model of Asthma Reveals the Anti-Inflammatory Pharmacophore". ACS Pharmacology & Translational Science. 4 (2): 488–502. doi:10.1021/acsptsci.0c00063. PMC 8033619. PMID 33860179.
  2. "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.