2C-O-4, also known as 4-isopropoxy-2,5-dimethoxyphenethylamine, is a phenethylamine of the 2C family.[1] It is also a positional isomer of isoproscaline and was probably first synthesized by Alexander Shulgin.[1] It produces hallucinogenic or psychedelic effects.[1] Because of the low potency of 2C-O-4, and the inactivity of 2C-O, Shulgin felt that the 2C-O series would not be an exciting area for research, and did not pursue any further analogues.[1]

Use and effects

Little is known about the psychopharmacological effects of 2C-O-4.[1] Based on the one report available in his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists 2C-O-4's dose as being greater than 60 mg orally.[1] At this dose, threshold psychoactive effects occurred.[1] These included awareness of something in the front part of the head, yawning, physiological changes, and a general exhilaration and excitement.[1] The effects lasted "a few hours" and were rated as a "plus-one" on the Shulgin Rating Scale.[1] The drug was regarded as remaining to be fully explored.[1]

Interactions

Pharmacology

Pharmacodynamics

The pharmacology of 2C-O-4 analogues has been studied.[2]

Chemistry

2C-O-4 is in a class of compounds commonly known as phenethylamines, and the systematic chemical name is 2-(4-isopropoxy-2,5-dimethoxyphenyl)ethanamine.[1]

Synthesis

The chemical synthesis of 2C-O-4 has been described.[1]

History

2C-O-4 was first described in the literature by Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) in 1991.[1]

Society and culture

Canada

As of October 31, 2016, 2C-O-4 is a controlled substance (Schedule III) in Canada.[3]

United States

2C-O-4 is unscheduled and unregulated in the United States; however, because of its close similarity in structure and effects to mescaline and 2C-T-7, possession and sale of 2C-O-4 may be subject to prosecution under the Federal Analog Act.

See also

References

source: https://en.wikipedia.org/wiki/2C-O-4