2C-G, or 2C-G-0, also known as 3,4-dimethyl-2,5-dimethoxyphenethylamine or as 3-methyl-2C-D, is a psychedelic phenethylamine of the 2C family.[1] First synthesized by Alexander Shulgin, it has structural and pharmacodynamic properties similar to 2C-D and Ganesha (G).[1] The drug has a number of known homologues, which are known as the 2C-G series of compounds.[1]
Use and effects
In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists 2C-G's dose range as 20 to 35 mg orally and its duration as 18 to 30 hours.[1] The time to peak effects was described as being 2 hours.[1] The effects of 2C-G have been reported to include little in the way of visuals, being a "true psychedelic", mental changes, insights, altered sense of taste, "energy tremor", stomach queasiness, and a feeling of heat in the upper back.[1] The drug is said to have very similar properties and effects as its amphetamine homologue Ganesha (G).[1] Its similar potency to Ganesha is in contrast to other 2Cs and psychedelic phenethylamines, which are less potent than their amphetamine homologues.[1]
Interactions
Chemistry
Synthesis
The chemical synthesis of 2C-G has been described.[1]
Homologues
Several homologues of 2C-G (2C-G-0) were also synthesized and/or tested by Alexander Shulgin.[1] These include 2C-G-3, 2C-G-5, and 2C-G-N.[1] Some, such as 2C-G-1, 2C-G-2, 2C-G-4, and 2C-G-6, are possible to synthesize in principle but impossible or extraordinarily difficult to do so in practice.[1]
| Compound | Details | Structure |
|---|---|---|
| 2C-G-1 | CAS #: 2888537-47-9 The synthesis of this compound has not been reported, but it is described prophetically in WO2022271982 |
 |
| 2C-G-2 | CAS #: 2888537-48-0 The synthesis of this compound has not been reported, but it is described prophetically in WO2022271982 |
 |
| 2C-G-3 | CAS #: 207740-19-0 Dose: 16–25 mg |
 |
| 2C-G-4 | CAS #: 952006-59-6 Partially synthesized but not tested. |
 |
| 2C-G-5 | CAS #: 207740-20-3 Dose: 10–16 mg |
 |
| 2C-G-6 | CAS #: 2888537-49-1 The synthesis of this compound has not been reported, but it is described prophetically in WO2022271982 |
 |
| 2C-G-N | CAS #: 207740-21-4 Dose: 20–40 mg |
 |
History
2C-G was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).[1]
Society and culture
Legal status
Canada
As of October 31, 2016; 2C-G is a controlled substance (Schedule III) in Canada.[2]
United Kingdom
2C-G and all other compounds featuring in PiHKAL are Class A drugs in the United Kingdom.
United States
In the United States 2C-G is considered a Schedule I controlled substance as a positional isomer of 2C-E and DOM.[3][4]
See also
- 2C (psychedelics)
- Ganesha (G)
- DOTMA (Julia)
References
- 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Shulgin AT, Shulgin A (1991). "2C-G". PiHKAL: A Chemical Love Story (1st ed.). Berkeley, CA: Transform Press. ISBN 978-0-9630096-0-9. OL 22859055M.
- ↑ "Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". 4 May 2016.
- ↑ "Lists of: Scheduling Actions - Controlled Substances - Regulated Chemicals" (PDF). Drug Enforcement Administration. February 2023.
- ↑ Drug Enforcement Administration (3 December 2007). "Definition of "Positional Isomer" as It Pertains to the Control of Schedule I Controlled Substances". Federal Register.