2C-B-AN, also known as 4-bromo-N-(α′-cyanobenzyl)-2,5-dimethoxyphenethylamine or as brolphetaminil, is a psychedelic drug of the phenethylamine, 2C, and N-benzylphenethylamine families related to 2C-B.[1][2][4] It is the derivative of 2C-B with a modified NBOMe-like N-(α′-cyanobenzyl) substitution.[1][2][4] The drug is chemically unstable and has been found to be a prodrug of 2C-B in vivo.[1][2][4] It is active at a dose of 50 mg orally and has a duration of 5 to 8 hours.[1][2][3] However, a wider dose range of 30 to 100 mg or more has also been reported.[3] 2C-B-AN has been described as producing stimulation and certain visual alterations.[1][3] It was described in the scientific literature by Daniel Trachsel in 2013, who cited personal communication with P. Rausch in 2009 as the source for the information.[1] 2C-B-AN was encountered as a novel designer drug in Europe by 2016.[2][3] It may be a controlled substance in Canada under phenethylamine blanket-ban language.[5] The drug is not an explicitly controlled substance in the United States.[6]

See also

References

  1. 1 2 3 4 5 6 7 8 Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. pp. 843–843. ISBN 978-3-03788-700-4. OCLC 858805226. Archived from the original on 21 August 2025.
  2. 1 2 3 4 5 6 7 8 Elliott SP, Holdbrook T, Brandt SD (May 2020). "Prodrugs of New Psychoactive Substances (NPS): A New Challenge". Journal of Forensic Sciences. 65 (3): 913–920. doi:10.1111/1556-4029.14268. PMID 31943218.
  3. 1 2 3 4 5 6 7 8 Trott DM (12 September 2022). "2C-B-AN". The Drug Users Bible [Extended Edition]. MxZero Publishing. ISBN 978-0-9955936-9-5. Retrieved 10 January 2026.
  4. 1 2 3 Ponce JD (2024). "The use of prodrugs as drugs of abuse". WIREs Forensic Science. 6 (3). doi:10.1002/wfs2.1514. ISSN 2573-9468. Retrieved 27 October 2025.
  5. "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
  6. Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026) (PDF), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026