1cP-MiPLA, also known as 1-cyclopropanoyl-MiPLA or 1-cyclopropanoyl-N-methyl-N-isopropyllysergamide, is a presumed psychedelic drug of the lysergamide family.[1][2][3] It is the 1-cyclopropanoyl derivative of MiPLA (N-methyl-N-isopropyllysergamide) and is thought to be a prodrug of MiPLA.[1][2][3] 1cP-MiPLA has been encountered as a novel designer drug online[1] and in Japan.[2][3]

Use and effects

1cP-MiPLA has been sold in the form of blotter tabs containing doses of 200 μg per tab.[1] Data on the effects of 1cP-MiPLA at different doses are not available.[1]

Interactions

Pharmacology

1cP-MiPLA is assumed to act as a prodrug of MiPLA via deacylation.[2][3] Relatedly, it is assumed to act as a serotonin receptor agonist, including of the serotonin 5-HT2A receptor, and to be a serotonergic psychedelic.[1]

Chemistry

Analogues

Analogues of 1cP-MiPLA include MiPLA, 1P-MiPLA, and 1cP-AL-LAD, among others.

History

1cP-MiPLA was first encountered as a novel designer drug online in 2020[1] and in Japan by 2022.[2][3]

Society and culture

Canada

1cP-MiPLA is not a controlled substance in Canada as of 2025.[4]

Russia

1cP-MiPLA is a schedule I controlled substance in Russia.[1]

United States

1cP-MiPLA is not an explicitly controlled substance in the United States.[5] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.

See also

References

  1. 1 2 3 4 5 6 7 8 9 "1cP-MIPLA". АИПСИН (in Russian). Retrieved 26 July 2025.
  2. 1 2 3 4 5 6 Tanaka R, Kawamura M, Mizutani S, Kikura-Hanajiri R (2022). "Analyses of LSD analogs in illegal products: The identification of 1cP-AL-LAD, 1cP-MIPLA and 1V-LSD". Toxicologie Analytique et Clinique. 34 (3): S171. Bibcode:2022ToxAC..34Q.171T. doi:10.1016/j.toxac.2022.06.295.
  3. 1 2 3 4 5 6 Tanaka R, Kawamura M, Mizutani S, Kikura-Hanajiri R (2023). "Identification of LSD analogs, 1cP-AL-LAD, 1cP-MIPLA, 1V-LSD and LSZ in sheet products" (PDF). Forensic Toxicology. 41 (2): 294–303. doi:10.1007/s11419-023-00661-1. ISSN 1860-8965. PMC 10310582. PMID 36809464. Retrieved 26 July 2025.
  4. ↑ "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
  5. ↑ Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026) (PDF), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026
source: https://en.wikipedia.org/wiki/1cP-MiPLA